STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kuDNA repair protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (300 aa)    
Predicted Functional Partners:
KKC24724.1
ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.993
KKC26005.1
ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.805
KKC24722.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.536
fieF
Ferrous iron transporter; Member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
       0.510
pdxH
Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
       0.510
KKC23735.1
Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.503
KKC25840.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.463
KKC25772.1
PhzF family phenazine biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.430
KKC26322.1
ErfK/YbiS/YcfS/YnhG; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.419
KKC24720.1
ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.410
Your Current Organism:
Sphingomonas sp. SRS2
NCBI taxonomy Id: 133190
Other names: S. sp. SRS2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.