STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
L336_0099Putative Peptidylprolyl isomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (175 aa)    
Predicted Functional Partners:
dnaK
Molecular chaperone; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.889
L336_0098
Putative thioredoxin reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.780
L336_0100
Exported protein of unknown function; No homology to any previously reported sequences.
       0.773
tgt
tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...]
    
  0.706
L336_0362
Putative DNA-directed DNA polymerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
   
 
 0.673
L336_0101
Putative NADH:ubiquinone reductase (H(+)-translocating); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.640
L336_0985
Hypothetical protein; No homology to any previously reported sequences.
  
 0.550
L336_0001
Hypothetical protein; No homology to any previously reported sequences.
  
 0.540
infA
Initiation factor IF-I; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
  
   0.525
L336_0102
Membrane protein of unknown function; No homology to any previously reported sequences.
       0.467
Your Current Organism:
Saccharimonas aalborgensis
NCBI taxonomy Id: 1332188
Other names: C. Saccharimonas aalborgensis, Candidatus Saccharimonas aalborgensis
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.