STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
htpXMembrane protease; Function of strongly homologous gene; enzyme; Belongs to the peptidase M48B family. (293 aa)    
Predicted Functional Partners:
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
     
 0.797
L336_0207
Homologs of previously reported genes of unknown function.
       0.779
L336_0209
Homologs of previously reported genes of unknown function.
  
    0.772
dnaJ
Co-factor of molecular chaperone; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwe [...]
  
 
 0.581
L336_0388
Membrane protein of unknown function; No homology to any previously reported sequences; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
  
 0.494
L336_0211
Hypothetical protein; No homology to any previously reported sequences.
     
 0.485
L336_0210
Hypothetical protein; No homology to any previously reported sequences.
       0.479
L336_0202
Ham1 family protein.
     
 0.472
L336_0205
Hypothetical protein; No homology to any previously reported sequences.
       0.453
L336_0203
ABC transporter permease.
       0.436
Your Current Organism:
Saccharimonas aalborgensis
NCBI taxonomy Id: 1332188
Other names: C. Saccharimonas aalborgensis, Candidatus Saccharimonas aalborgensis
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