STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
L336_0595Putative Dephospho-CoA kinase-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (189 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; Function of strongly homologous gene; enzyme.
  
  
 0.845
mutM
formamidopyrimidine-DNA glycosidase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
  
  
 0.650
def
Putative Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
       0.580
leuS
leucyl-tRNA synthetase; Function of strongly homologous gene; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.570
pheT
Phenylalanine--tRNA ligase beta subunit; Function of strongly homologous gene; enzyme; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
     
 0.560
rnhB
Putative Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the UPF0102 family.
  
    0.492
L336_0098
Putative thioredoxin reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.449
L336_0945
Homologs of previously reported genes of unknown function.
 
     0.445
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
 
  
 0.409
L336_0257
Homologs of previously reported genes of unknown function.
  
     0.400
Your Current Organism:
Saccharimonas aalborgensis
NCBI taxonomy Id: 1332188
Other names: C. Saccharimonas aalborgensis, Candidatus Saccharimonas aalborgensis
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