STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
L336_0945Homologs of previously reported genes of unknown function. (239 aa)    
Predicted Functional Partners:
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
    
 0.929
L336_0668
Putative Nucleoside diphosphate kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 
 0.928
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
  
 
 0.923
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
  
 0.848
L336_0946
Hypothetical protein; No homology to any previously reported sequences.
       0.642
L336_0949
Putative Dihydrofolate reductase type 3; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
     
 0.528
L336_0948
Hypothetical protein; No homology to any previously reported sequences.
       0.525
L336_0947
Hypothetical protein; No homology to any previously reported sequences.
       0.509
polA
DNA polymerase I; Function of strongly homologous gene; enzyme.
     
 0.456
L336_0595
Putative Dephospho-CoA kinase-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
     0.445
Your Current Organism:
Saccharimonas aalborgensis
NCBI taxonomy Id: 1332188
Other names: C. Saccharimonas aalborgensis, Candidatus Saccharimonas aalborgensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.