STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
U5DIX5_AMBTCDNA helicase; Belongs to the MCM family. (828 aa)    
Predicted Functional Partners:
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
  
0.998
W1P0N2_AMBTC
DNA helicase; Belongs to the MCM family.
   
0.998
W1PSV0_AMBTC
DNA helicase; Belongs to the MCM family.
   
0.998
W1NL82_AMBTC
DNA helicase; Belongs to the MCM family.
  
0.994
W1NWZ0_AMBTC
MCM domain-containing protein.
  
0.993
W1NTJ8_AMBTC
Zf-primase domain-containing protein.
   
 0.987
W1PPV7_AMBTC
Cell division control protein; Belongs to the CDC6/cdc18 family.
   
 0.987
W1NNE1_AMBTC
AAA_16 domain-containing protein.
   
 0.981
W1PEG8_AMBTC
DNA helicase; Belongs to the MCM family.
  
0.979
W1NHX4_AMBTC
MCM domain-containing protein; Belongs to the MCM family.
   
0.978
Your Current Organism:
Amborella trichopoda
NCBI taxonomy Id: 13333
Other names: A. trichopoda, Amborella trichopoda Baill.
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