STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BB560_002400Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (561 aa)    
Predicted Functional Partners:
BB560_000427
Uncharacterized protein.
 
 0.985
BB560_001156
Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
  
 
 0.941
BB560_005779
Uncharacterized protein.
  
 
 0.897
BB560_003053
AB hydrolase-1 domain-containing protein.
   
 0.882
BB560_002454
A_deaminase domain-containing protein; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
  
 0.838
BB560_004548
Peptidase_M24 domain-containing protein.
  
 
 0.825
BB560_003071
Pribosyltran domain-containing protein.
  
 
 0.824
BB560_002832
PRAI domain-containing protein.
  
 
 0.817
BB560_001958
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
  
 0.816
BB560_001482
SH3 domain-containing protein.
  
 
 0.799
Your Current Organism:
Smittium megazygosporum
NCBI taxonomy Id: 133381
Other names: S. megazygosporum
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