STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AYI68_g1888Putative GTP cyclohydrolase-2. (380 aa)    
Predicted Functional Partners:
AYI68_g3006
Riboflavin synthase.
 0.994
AYI68_g8
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
 
   
 0.963
AYI68_g8221
6,7-dimethyl-8-ribityllumazine synthase.
 
 
 0.956
AYI68_g1211
Uncharacterized protein.
  
 0.841
AYI68_g4007
Nucleoside diphosphate kinase.
  
 0.805
AYI68_g466
GTP cyclohydrolase 1.
   
 
 0.785
AYI68_g5010
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
     
 0.761
AYI68_g2305
2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase.
    
 0.758
AYI68_g2304
Uncharacterized protein.
    
 0.758
AYI68_g234
Riboflavin kinase.
  
 0.723
Your Current Organism:
Smittium mucronatum
NCBI taxonomy Id: 133383
Other names: S. mucronatum
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.