M2A_0157 protein (Tepidicaulis marinus) - STRING interaction network

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Score

M2A_0157

D-isomer specific 2-hydroxyacid dehydrogenase family protein. (329 aa)

Predicted Functional Partners:

M2A_2936

0.951

M2A_0287

0.862

rplF

0.849

rplB

0.811

cysC

0.803

rplQ

0.788

rplP

0.784

rplV

0.771

rplM

0.767

rpmA

0.767

Your Current Organism:

Tepidicaulis marinus

NCBI taxonomy Id: 1333998
Other names: DSM 27167, NBRC 109643, T. marinus, Tepidicaulis marinus Takeuchi et al. 2015, alpha proteobacterium MA2, strain MA2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
M2A_0157	M2A_0287	M2A_0157	M2A_0287	D-isomer specific 2-hydroxyacid dehydrogenase family protein.	Malic enzyme.	0.862
M2A_0157	M2A_2936	M2A_0157	M2A_2936	D-isomer specific 2-hydroxyacid dehydrogenase family protein.	Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.	0.951
M2A_0157	cysC	M2A_0157	M2A_0463	D-isomer specific 2-hydroxyacid dehydrogenase family protein.	Sulfate adenylyltransferase large subunit; Catalyzes the synthesis of activated sulfate. Belongs to the APS kinase family.	0.803
M2A_0157	rplB	M2A_0157	M2A_2926	D-isomer specific 2-hydroxyacid dehydrogenase family protein.	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	0.811
M2A_0157	rplF	M2A_0157	M2A_2914	D-isomer specific 2-hydroxyacid dehydrogenase family protein.	50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.	0.849
M2A_0157	rplM	M2A_0157	M2A_0592	D-isomer specific 2-hydroxyacid dehydrogenase family protein.	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.767
M2A_0157	rplP	M2A_0157	M2A_2922	D-isomer specific 2-hydroxyacid dehydrogenase family protein.	50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.	0.784
M2A_0157	rplQ	M2A_0157	M2A_2904	D-isomer specific 2-hydroxyacid dehydrogenase family protein.	50S ribosomal protein L17.	0.788
M2A_0157	rplV	M2A_0157	M2A_2924	D-isomer specific 2-hydroxyacid dehydrogenase family protein.	50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.	0.771
M2A_0157	rpmA	M2A_0157	M2A_0829	D-isomer specific 2-hydroxyacid dehydrogenase family protein.	50S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.	0.767
M2A_0287	M2A_0157	M2A_0287	M2A_0157	Malic enzyme.	D-isomer specific 2-hydroxyacid dehydrogenase family protein.	0.862
M2A_2936	M2A_0157	M2A_2936	M2A_0157	Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.	D-isomer specific 2-hydroxyacid dehydrogenase family protein.	0.951
M2A_2936	rplV	M2A_2936	M2A_2924	Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.	50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.	0.503
cysC	M2A_0157	M2A_0463	M2A_0157	Sulfate adenylyltransferase large subunit; Catalyzes the synthesis of activated sulfate. Belongs to the APS kinase family.	D-isomer specific 2-hydroxyacid dehydrogenase family protein.	0.803
rplB	M2A_0157	M2A_2926	M2A_0157	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	D-isomer specific 2-hydroxyacid dehydrogenase family protein.	0.811
rplB	rplF	M2A_2926	M2A_2914	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.	0.999
rplB	rplM	M2A_2926	M2A_0592	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.999
rplB	rplP	M2A_2926	M2A_2922	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.	0.999
rplB	rplQ	M2A_2926	M2A_2904	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L17.	0.998
rplB	rplV	M2A_2926	M2A_2924	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.	0.999