node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
M2A_0649 | M2A_0652 | M2A_0649 | M2A_0652 | Signal peptidase I; Belongs to the peptidase S26 family. | Conserved protein. | 0.509 |
M2A_0649 | acpS | M2A_0649 | M2A_0650 | Signal peptidase I; Belongs to the peptidase S26 family. | 4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | 0.574 |
M2A_0649 | era | M2A_0649 | M2A_0647 | Signal peptidase I; Belongs to the peptidase S26 family. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.866 |
M2A_0649 | pdxJ | M2A_0649 | M2A_0651 | Signal peptidase I; Belongs to the peptidase S26 family. | Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.629 |
M2A_0649 | pyrE | M2A_0649 | M2A_0653 | Signal peptidase I; Belongs to the peptidase S26 family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.446 |
M2A_0649 | rnc | M2A_0649 | M2A_0648 | Signal peptidase I; Belongs to the peptidase S26 family. | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.980 |
M2A_0652 | M2A_0649 | M2A_0652 | M2A_0649 | Conserved protein. | Signal peptidase I; Belongs to the peptidase S26 family. | 0.509 |
M2A_0652 | acpS | M2A_0652 | M2A_0650 | Conserved protein. | 4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | 0.702 |
M2A_0652 | era | M2A_0652 | M2A_0647 | Conserved protein. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.509 |
M2A_0652 | pdxJ | M2A_0652 | M2A_0651 | Conserved protein. | Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.702 |
M2A_0652 | pyrE | M2A_0652 | M2A_0653 | Conserved protein. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.614 |
M2A_0652 | rnc | M2A_0652 | M2A_0648 | Conserved protein. | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.509 |
M2A_2502 | acpS | M2A_2502 | M2A_0650 | CutA1 divalent ion tolerance protein. | 4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | 0.552 |
M2A_3052 | acpS | M2A_3052 | M2A_0650 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | 0.611 |
acpP | acpS | M2A_1183 | M2A_0650 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | 0.983 |
acpP | coaE | M2A_1183 | M2A_0211 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.686 |
acpP | rnc | M2A_1183 | M2A_0648 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.895 |
acpS | M2A_0649 | M2A_0650 | M2A_0649 | 4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | Signal peptidase I; Belongs to the peptidase S26 family. | 0.574 |
acpS | M2A_0652 | M2A_0650 | M2A_0652 | 4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | Conserved protein. | 0.702 |
acpS | M2A_2502 | M2A_0650 | M2A_2502 | 4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | CutA1 divalent ion tolerance protein. | 0.552 |