STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nnrECarbohydrate kinase, YjeF-like protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the [...] (488 aa)    
Predicted Functional Partners:
M2A_1096
DEAD/DEAH box helicase domain-containing protein; Belongs to the DEAD box helicase family.
   
 0.975
M2A_3230
DEAD/DEAH box helicase domain protein.
   
 0.975
M2A_0528
NUDIX hydrolase.
  
 0.969
rppH
NUDIX hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.
  
 0.969
M2A_3302
NUDIX hydrolase.
  
 0.969
M2A_3303
NUDIX hydrolase.
  
 0.969
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
   0.881
M2A_2810
Conserved protein.
 
 
 0.826
M2A_0716
RNA methyltransferase, TrmH family.
   
 
 0.771
M2A_2485
RNA methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
   
 
 0.771
Your Current Organism:
Tepidicaulis marinus
NCBI taxonomy Id: 1333998
Other names: DSM 27167, NBRC 109643, T. marinus, Tepidicaulis marinus Takeuchi et al. 2015, alpha proteobacterium MA2, strain MA2
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