STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
M2A_1814NUDIX hydrolase. (314 aa)    
Predicted Functional Partners:
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.861
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
   
 
  0.806
M2A_0573
Silent information regulator protein Sir2.
    
 0.805
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
     
 0.797
M2A_1567
Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family.
     
 0.785
nadK
NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.785
M2A_0763
CinA domain-containing protein; Belongs to the CinA family.
     
 0.783
M2A_0987
CinA domain-containing protein; Belongs to the CinA family.
     
 0.783
M2A_3227
MazG family protein.
     
 0.617
M2A_1460
Riboflavin biosynthesis protein RibF; Belongs to the ribF family.
  
 
 0.608
Your Current Organism:
Tepidicaulis marinus
NCBI taxonomy Id: 1333998
Other names: DSM 27167, NBRC 109643, T. marinus, Tepidicaulis marinus Takeuchi et al. 2015, alpha proteobacterium MA2, strain MA2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.