STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
M2A_2308Conserved protein. (168 aa)    
Predicted Functional Partners:
M2A_1293
Putative Chase2 sensor protein.
 
  
  0.875
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
  0.857
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
    0.744
M2A_1723
Patatin.
  
 
   0.707
M2A_2309
Fmu (Sun) domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
    0.585
M2A_0452
Conserved protein.
 
     0.536
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.524
M2A_0139
PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase.
    
 0.520
M2A_2027
Alpha/beta hydrolase fold protein.
  
     0.456
M2A_2972
CheR methyltransferase, SAM binding domain protein.
    
  0.448
Your Current Organism:
Tepidicaulis marinus
NCBI taxonomy Id: 1333998
Other names: DSM 27167, NBRC 109643, T. marinus, Tepidicaulis marinus Takeuchi et al. 2015, alpha proteobacterium MA2, strain MA2
Server load: low (12%) [HD]