STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
M2A_2389uroporphyrin-III methylase, involved in siroheme cofactor synthesis for assimilatory nitrite reductase; Belongs to the precorrin methyltransferase family. (255 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.996
M2A_0626
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.945
M2A_2891
Siroheme synthase.
 
 
 0.944
M2A_1633
Sulfite reductase.
 
  
 0.928
M2A_2387
Assimilatory nitrite reductase small subunit.
  
  
 0.922
M2A_2890
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite.
 
  
 0.920
cysC
Sulfate adenylyltransferase large subunit; Catalyzes the synthesis of activated sulfate. Belongs to the APS kinase family.
 
  
 0.907
M2A_2386
Nitrite reductase (NAD(P)H), large subunit; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.874
M2A_0464
Sulfate adenylyltransferase subunit 2.
 
  
 0.864
M2A_2383
Nitrate transporter.
  
  
 0.800
Your Current Organism:
Tepidicaulis marinus
NCBI taxonomy Id: 1333998
Other names: DSM 27167, NBRC 109643, T. marinus, Tepidicaulis marinus Takeuchi et al. 2015, alpha proteobacterium MA2, strain MA2
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