STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AYI70_g12032Ubiquitin-activating enzyme E1-like. (723 aa)    
Predicted Functional Partners:
AYI69_g2437
Putative small nuclear ribonucleoprotein F.
   
 0.981
AYI70_g2951
NEDD8-conjugating enzyme ubc12; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.870
AYI70_g9110
Autophagy-related protein.
   
 0.855
AYI70_g11947
Autophagy-related protein 3.
    
 0.850
AYI70_g1435
Ubiquitin-conjugating enzyme E2-18 kDa; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.769
URM1
Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target pr [...]
   
 0.740
AYI70_g10528
JmjC domain-containing histone demethylation protein 1.
    
 0.725
AYI70_g10089
tRNA threonylcarbamoyladenosine dehydratase.
 
 
 0.697
AYI70_g5751
tRNA threonylcarbamoyladenosine dehydratase.
 
 
 0.695
AYI70_g11522
Ubiquitin-60S ribosomal protein L40.
   
 0.687
Your Current Organism:
Smittium culicis
NCBI taxonomy Id: 133412
Other names: S. culicis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.