STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AYI70_g11520ATP-dependent DNA helicase; Belongs to the helicase family. (295 aa)    
Predicted Functional Partners:
AYI69_g5718
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 
 0.978
AYI70_g3747
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
   
 
 0.965
AYI70_g1649
ATP-dependent DNA helicase hus2/rqh1.
  
 
 0.924
AYI70_g3968
DNA repair and recombination protein RAD52.
    
 
 0.911
AYI70_g11513
DNA replication ATP-dependent helicase/nuclease DNA2.
    
 
 0.863
AYI70_g9265
DNA replication ATP-dependent helicase/nuclease DNA2.
    
 
 0.863
AYI70_g12335
DNA helicase II.
  
 
 0.837
AYI70_g11515
DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.
  
 
 0.818
AYI70_g4643
Topoisomerase 1-associated factor 1.
    
 
 0.798
AYI70_g9519
Histone chaperone asf1.
   
 
 0.766
Your Current Organism:
Smittium culicis
NCBI taxonomy Id: 133412
Other names: S. culicis
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.