STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AYI70_g10684SET domain-containing protein. (729 aa)    
Predicted Functional Partners:
AYI70_g5996
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...]
    
 0.753
AYI70_g6016
Phosphoinositide phospholipase C.
    
 0.741
AYI70_g758
Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
     
 0.697
AYI70_g1406
Putative inositol polyphosphate 5-phosphatase.
     
 0.617
AYI70_g12079
Inositol-1,4,5-trisphosphate 5-phosphatase 1.
     
 0.562
AYI70_g8759
Transcription factor prr1.
    
 0.527
AYI70_g10407
Hybrid signal transduction histidine kinase K.
    
 0.523
AYI70_g1216
Hybrid signal transduction histidine kinase K.
    
 0.523
AYI70_g10773
Protein-serine/threonine kinase.
    
 0.497
AYI70_g4129
Protein-serine/threonine kinase.
    
 0.497
Your Current Organism:
Smittium culicis
NCBI taxonomy Id: 133412
Other names: S. culicis
Server load: low (26%) [HD]