STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AYI69_g9004Histone H2A; Belongs to the histone H2A family. (135 aa)    
Predicted Functional Partners:
AYI70_g4759
Histone H2B; Belongs to the histone H2B family.
 
 0.999
AYI70_g2125
Histone H2A deubiquitinase MYSM1.
    
 0.999
AYI69_g4659
Histone H3; Belongs to the histone H3 family.
 
 
 0.998
AYI69_g2624
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.997
AYI69_g7745
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.997
AYI70_g10377
Histone H2A; Belongs to the histone H2A family.
  
0.995
AYI69_g10355
Ubiquitin-40S ribosomal protein S27a.
   
 0.994
AYI70_g9432
Polyubiquitin.
   
 0.993
AYI70_g12226
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.991
AYI70_g736
Uncharacterized protein.
    
 0.991
Your Current Organism:
Smittium culicis
NCBI taxonomy Id: 133412
Other names: S. culicis
Server load: low (18%) [HD]