STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AYI70_g4672Uncharacterized protein. (452 aa)    
Predicted Functional Partners:
AYI70_g170
TFIID_20kDa domain-containing protein.
    
 0.959
AYI70_g12462
SAGA-associated factor 73.
    
 0.958
AYI70_g11182
Transcription initiation factor TFIID subunit 9.
    
 0.958
AYI70_g9585
Chromatin-remodeling complexes subunit ngg1.
    
 0.957
AYI70_g12293
Uncharacterized protein.
    
 0.956
AYI70_g3693
SAGA complex subunit spt3.
    
 0.951
AYI70_g1069
Transcriptional activator spt7.
   
 0.943
AYI70_g5666
Histone acetyltransferase GCN5.
    
 0.939
AYI70_g944
Transcriptional adapter 2; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation.
    
 0.939
SUS1
Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...]
    
 0.938
Your Current Organism:
Smittium culicis
NCBI taxonomy Id: 133412
Other names: S. culicis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.