STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AYI70_g3947Transcription elongation factor spt-6. (1636 aa)    
Predicted Functional Partners:
AYI70_g4656
Transcription elongation factor S-II.
    
 0.999
AYI70_g2502
RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.
     
 0.999
AYI70_g60
Transcription factor IWS1.
   
 0.999
AYI70_g4046
FACT complex subunit spt16.
   
 0.997
AYI70_g3720
FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]
   
 0.996
AYI70_g4250
Transcription elongation factor spt5.
   
 0.994
AYI70_g2214
Uncharacterized protein.
   
 0.992
AYI70_g10386
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
    
 0.991
AYI70_g12226
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.988
AYI70_g1052
Cell division control protein 73.
   
 0.986
Your Current Organism:
Smittium culicis
NCBI taxonomy Id: 133412
Other names: S. culicis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.