STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AYI70_g2132NAD-dependent histone deacetylase HST3. (737 aa)    
Predicted Functional Partners:
AYI70_g8759
Transcription factor prr1.
    
 0.999
AYI69_g4659
Histone H3; Belongs to the histone H3 family.
    
 0.925
AYI70_g5
NAD-dependent protein deacetylase sirtuin-2.
    
 0.868
AYI70_g4712
NAD-dependent histone deacetylase sir2.
  
 
0.830
AYI70_g10672
Ribosomal RNA-processing protein 8; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2. Belongs to the methyltransferase superfamily. RRP8 family.
    
 0.823
AYI70_g5268
Peroxisomal NADH pyrophosphatase NUDT12.
    
 0.821
AYI69_g2624
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.797
AYI69_g7745
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.797
AYI70_g5913
Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family.
   
 0.796
AYI70_g2488
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2.
   
 0.796
Your Current Organism:
Smittium culicis
NCBI taxonomy Id: 133412
Other names: S. culicis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.