Avbf_17402 protein (Armadillidium vulgare) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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Score

Avbf_17402

Neuroendocrine protein 7B2. (196 aa)

Predicted Functional Partners:

Avbf_17228

0.941

Avbf_01137

0.710

Avbf_08970

0.645

Avbf_14539

0.547

Avbf_09516

0.547

Avbf_02711

0.519

Avbf_02709

0.519

Avbf_02708

0.519

Avbf_02710

0.519

Avbf_12049

0.519

Your Current Organism:

Armadillidium vulgare

NCBI taxonomy Id: 13347
Other names: A. vulgare, common pillbug

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Avbf_01137	Avbf_17402	A0A444TFQ7	A0A444SIY5	Peptidyl-alpha-hydroxyglycine alpha-amidating lyase 2.	Neuroendocrine protein 7B2.	0.710
Avbf_02708	Avbf_02709	A0A444SMB4	A0A444SMA6	Proprotein convertase subtilisin/kexin type 5.	FRAS1-related extracellular matrix protein 3.	0.711
Avbf_02708	Avbf_02710	A0A444SMB4	A0A444SMB7	Proprotein convertase subtilisin/kexin type 5.	Uncharacterized protein.	0.700
Avbf_02708	Avbf_02711	A0A444SMB4	A0A444SMA3	Proprotein convertase subtilisin/kexin type 5.	Extracellular matrix protein FRAS1.	0.713
Avbf_02708	Avbf_09516	A0A444SMB4	A0A444TQY3	Proprotein convertase subtilisin/kexin type 5.	Membrane-bound transcription factor site-1 protease.	0.495
Avbf_02708	Avbf_12049	A0A444SMB4	A0A444SNP8	Proprotein convertase subtilisin/kexin type 5.	Furin-like protease 1, isoform 1-CRR; Belongs to the peptidase S8 family.	0.446
Avbf_02708	Avbf_14539	A0A444SMB4	A0A444T7J5	Proprotein convertase subtilisin/kexin type 5.	Membrane-bound transcription factor site-1 protease.	0.495
Avbf_02708	Avbf_17228	A0A444SMB4	A0A444SKI1	Proprotein convertase subtilisin/kexin type 5.	Neuroendocrine convertase 2.	0.508
Avbf_02708	Avbf_17402	A0A444SMB4	A0A444SIY5	Proprotein convertase subtilisin/kexin type 5.	Neuroendocrine protein 7B2.	0.519
Avbf_02709	Avbf_02708	A0A444SMA6	A0A444SMB4	FRAS1-related extracellular matrix protein 3.	Proprotein convertase subtilisin/kexin type 5.	0.711
Avbf_02709	Avbf_02710	A0A444SMA6	A0A444SMB7	FRAS1-related extracellular matrix protein 3.	Uncharacterized protein.	0.791
Avbf_02709	Avbf_02711	A0A444SMA6	A0A444SMA3	FRAS1-related extracellular matrix protein 3.	Extracellular matrix protein FRAS1.	0.979
Avbf_02709	Avbf_09516	A0A444SMA6	A0A444TQY3	FRAS1-related extracellular matrix protein 3.	Membrane-bound transcription factor site-1 protease.	0.495
Avbf_02709	Avbf_12049	A0A444SMA6	A0A444SNP8	FRAS1-related extracellular matrix protein 3.	Furin-like protease 1, isoform 1-CRR; Belongs to the peptidase S8 family.	0.446
Avbf_02709	Avbf_14539	A0A444SMA6	A0A444T7J5	FRAS1-related extracellular matrix protein 3.	Membrane-bound transcription factor site-1 protease.	0.495
Avbf_02709	Avbf_17228	A0A444SMA6	A0A444SKI1	FRAS1-related extracellular matrix protein 3.	Neuroendocrine convertase 2.	0.508
Avbf_02709	Avbf_17402	A0A444SMA6	A0A444SIY5	FRAS1-related extracellular matrix protein 3.	Neuroendocrine protein 7B2.	0.519
Avbf_02710	Avbf_02708	A0A444SMB7	A0A444SMB4	Uncharacterized protein.	Proprotein convertase subtilisin/kexin type 5.	0.700
Avbf_02710	Avbf_02709	A0A444SMB7	A0A444SMA6	Uncharacterized protein.	FRAS1-related extracellular matrix protein 3.	0.791
Avbf_02710	Avbf_02711	A0A444SMB7	A0A444SMA3	Uncharacterized protein.	Extracellular matrix protein FRAS1.	0.854

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Network Stats

number of nodes:

11

number of edges:

25

average node degree:

4.55

avg. local clustering coefficient:

0.885

expected number of edges:

11

PPI enrichment p-value:

0.000195

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0001732

Formation of cytoplasmic translation initiation complex

10 of 16

2.95

12.23

1.43e-24

GO:0006446

Regulation of translational initiation

3 of 19

2.35

2.27

4.70e-05

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003743

Translation initiation factor activity

11 of 44

2.55

11.02

6.93e-25

GO:0031369

Translation initiation factor binding

2 of 20

2.15

0.89

0.0217

GO:0003723

RNA binding

5 of 678

1.02

0.65

0.0139

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0033290

Eukaryotic 48S preinitiation complex

11 of 15

3.02

14.64

2.50e-29

GO:0005852

Eukaryotic translation initiation factor 3 complex

10 of 14

3.0

13.14

3.29e-26

GO:0016282

Eukaryotic 43S preinitiation complex

10 of 18

2.9

12.54

1.65e-25

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:7924

Translation preinitiation complex

11 of 20

2.89

13.62

6.42e-28

CL:7926

Eukaryotic translation initiation factor 3 complex

10 of 12

3.07

13.34

2.54e-26

CL:7938

Eukaryotic translation initiation factor 3 complex

5 of 6

3.07

5.93

1.15e-11

CL:7927

Eukaryotic translation initiation factor 3 complex

5 of 6

3.07

5.93

1.15e-11

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03013

RNA transport

9 of 180

1.85

4.61

4.04e-14

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-72695

Formation of the ternary complex, and subsequently, the 43S complex

11 of 49

2.5

10.67

1.46e-24

MAP-72649

Translation initiation complex formation

11 of 56

2.44

10.29

2.74e-24

MAP-72702

Ribosomal scanning and start codon recognition

11 of 58

2.43

10.21

2.74e-24

MAP-72662

Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S

11 of 59

2.42

10.17

2.74e-24

MAP-156827

L13a-mediated translational silencing of Ceruloplasmin expression

11 of 102

2.18

8.15

4.95e-22

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005852

Eukaryotic translation initiation factor 3 complex

9 of 13

2.99

11.24

2.49e-22

GOCC:0071541

Eukaryotic translation initiation factor 3 complex, eIF3m

3 of 4

3.03

2.86

6.15e-06

GOCC:0071540

Eukaryotic translation initiation factor 3 complex, eIF3e

2 of 2

3.15

1.74

0.00073

GOCC:0043614

multi-eIF complex

2 of 2

3.15

1.74

0.00073

GOCC:0070993

Translation preinitiation complex

2 of 4

2.85

1.59

0.0013

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0396

Initiation factor

8 of 19

2.77

9.11

1.14e-18

KW-0963

Cytoplasm

8 of 161

1.85

4.21

2.32e-12

KW-0694

RNA-binding

3 of 191

1.35

0.76

0.0194

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR000717

Proteasome component (PCI) domain

4 of 18

2.5

2.87

3.75e-06

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00088

Motif in proteasome subunits, Int-6, Nip-1 and TRIP-15

3 of 13

2.51

2.21

7.67e-05

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