Avbf_14461 protein (Armadillidium vulgare) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

Your Input:

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Coexpression

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[Homology]

Score

Avbf_14461

1,5-anhydro-D-fructose reductase. (305 aa)

Predicted Functional Partners:

Avbf_06035

0.927

Avbf_14546

0.778

Avbf_15301

0.771

Avbf_16539

0.771

Avbf_18502

0.771

Avbf_00227

0.756

Avbf_12601

0.721

Avbf_13248

0.699

Avbf_13249

0.699

Avbf_13339

0.699

Your Current Organism:

Armadillidium vulgare

NCBI taxonomy Id: 13347
Other names: A. vulgare, common pillbug

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Avbf_00227	Avbf_14461	A0A444TKH1	A0A444T4V8	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	1,5-anhydro-D-fructose reductase.	0.756
Avbf_00227	Avbf_14546	A0A444TKH1	A0A444SVT6	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	Methylmalonic aciduria and homocystinuria type C protein-like.	0.756
Avbf_00227	Avbf_15301	A0A444TKH1	A0A444SY30	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	L-galactose dehydrogenase.	0.787
Avbf_00227	Avbf_16539	A0A444TKH1	A0A444T3Y2	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	L-galactose dehydrogenase.	0.787
Avbf_00227	Avbf_18502	A0A444TKH1	A0A444TBT4	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	L-galactose dehydrogenase.	0.787
Avbf_06035	Avbf_12601	A0A444SUJ8	A0A444T8H8	Glutamate--cysteine ligase.	Glutathione synthetase.	0.977
Avbf_06035	Avbf_14461	A0A444SUJ8	A0A444T4V8	Glutamate--cysteine ligase.	1,5-anhydro-D-fructose reductase.	0.927
Avbf_06035	Avbf_14546	A0A444SUJ8	A0A444SVT6	Glutamate--cysteine ligase.	Methylmalonic aciduria and homocystinuria type C protein-like.	0.927
Avbf_12601	Avbf_06035	A0A444T8H8	A0A444SUJ8	Glutathione synthetase.	Glutamate--cysteine ligase.	0.977
Avbf_12601	Avbf_14461	A0A444T8H8	A0A444T4V8	Glutathione synthetase.	1,5-anhydro-D-fructose reductase.	0.721
Avbf_12601	Avbf_14546	A0A444T8H8	A0A444SVT6	Glutathione synthetase.	Methylmalonic aciduria and homocystinuria type C protein-like.	0.717
Avbf_13248	Avbf_13249	A0A444SDM4	A0A444SDM7	Glyoxylate reductase/hydroxypyruvate reductase.	Glyoxylate/hydroxypyruvate reductase HPR3; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.791
Avbf_13248	Avbf_14461	A0A444SDM4	A0A444T4V8	Glyoxylate reductase/hydroxypyruvate reductase.	1,5-anhydro-D-fructose reductase.	0.699
Avbf_13248	Avbf_14546	A0A444SDM4	A0A444SVT6	Glyoxylate reductase/hydroxypyruvate reductase.	Methylmalonic aciduria and homocystinuria type C protein-like.	0.682
Avbf_13248	Avbf_15301	A0A444SDM4	A0A444SY30	Glyoxylate reductase/hydroxypyruvate reductase.	L-galactose dehydrogenase.	0.685
Avbf_13248	Avbf_16539	A0A444SDM4	A0A444T3Y2	Glyoxylate reductase/hydroxypyruvate reductase.	L-galactose dehydrogenase.	0.685
Avbf_13248	Avbf_18502	A0A444SDM4	A0A444TBT4	Glyoxylate reductase/hydroxypyruvate reductase.	L-galactose dehydrogenase.	0.685
Avbf_13249	Avbf_13248	A0A444SDM7	A0A444SDM4	Glyoxylate/hydroxypyruvate reductase HPR3; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Glyoxylate reductase/hydroxypyruvate reductase.	0.791
Avbf_13249	Avbf_14461	A0A444SDM7	A0A444T4V8	Glyoxylate/hydroxypyruvate reductase HPR3; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	1,5-anhydro-D-fructose reductase.	0.699
Avbf_13249	Avbf_14546	A0A444SDM7	A0A444SVT6	Glyoxylate/hydroxypyruvate reductase HPR3; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Methylmalonic aciduria and homocystinuria type C protein-like.	0.682

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Network Stats

number of nodes:

11

number of edges:

30

average node degree:

5.45

avg. local clustering coefficient:

0.814

expected number of edges:

11

PPI enrichment p-value:

2.02e-06

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0055085

Transmembrane transport

10 of 446

1.13

1.52

8.02e-09

GO:0006810

Transport

11 of 578

1.06

1.38

3.59e-09

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0015423

ABC-type maltose transporter activity

5 of 8

2.58

4.33

4.72e-09

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016021

Integral component of membrane

10 of 1090

0.74

0.69

2.10e-05

GO:0005886

Plasma membrane

11 of 1625

0.61

0.55

2.10e-05

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:8964

Mixed, incl. ABC-type maltose transporter activity, and Bacterial extracellular solute-binding protein

11 of 32

2.32

8.96

3.00e-22

CL:8966

Mixed, incl. ABC-type maltose transporter activity, and Bacterial extracellular solute-binding protein

7 of 22

2.28

5.51

1.30e-12

CL:8968

Mixed, incl. ABC-type maltose transporter activity, and MalK, OB fold domain

6 of 15

2.38

5.04

4.99e-11

CL:8970

Mixed, incl. MalK, OB fold domain, and ABC-type maltose transporter activity

2 of 8

2.18

0.88

0.0228

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02010

ABC transporters

11 of 318

1.32

2.34

5.42e-13

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0043190

ATP-binding cassette (ABC) transporter complex

11 of 63

2.02

6.73

5.02e-20

GOCC:0055052

ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

6 of 37

1.99

3.9

7.64e-10

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0813

Transport

10 of 197

1.49

2.91

1.63e-12

KW-1003

Cell membrane

10 of 212

1.45

2.79

1.66e-12

KW-0762

Sugar transport

2 of 6

2.3

1.39

0.0025

KW-1133

Transmembrane helix

10 of 1143

0.72

0.67

1.62e-05

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00528

Binding-protein-dependent transport system inner membrane component

10 of 58

2.02

6.0

5.23e-17

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR035906

MetI-like superfamily

10 of 58

2.02

5.91

1.31e-16

IPR000515

ABC transporter type 1, transmembrane domain MetI-like

10 of 58

2.02

5.91

1.31e-16

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