Avbf_02723 protein (Armadillidium vulgare) - STRING interaction network

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Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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Score

Avbf_02723

Non-lysosomal glucosylceramidase. (477 aa)

Predicted Functional Partners:

Avbf_09211

0.994

Avbf_01595

0.971

Avbf_03973

0.970

Avbf_08560

0.967

Avbf_13921

0.957

Avbf_06543

0.957

Avbf_08180

0.953

Avbf_12524

0.952

Avbf_12527

0.952

Avbf_08881

0.950

Your Current Organism:

Armadillidium vulgare

NCBI taxonomy Id: 13347
Other names: A. vulgare, common pillbug

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Avbf_01595	Avbf_02723	A0A444TSH6	A0A444T7R8	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	Non-lysosomal glucosylceramidase.	0.971
Avbf_01595	Avbf_03973	A0A444TSH6	A0A444SYM6	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.999
Avbf_01595	Avbf_06543	A0A444TSH6	A0A444TQZ2	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-2 complex subunit mu; Belongs to the adaptor complexes medium subunit family.	0.903
Avbf_01595	Avbf_08560	A0A444TSH6	A0A444T6T8	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-3 complex subunit beta-1.	0.886
Avbf_01595	Avbf_08881	A0A444TSH6	A0A444T5B5	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	Clathrin heavy chain 1.	0.913
Avbf_01595	Avbf_09211	A0A444TSH6	A0A444T5Y5	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	Cyclin-G-associated kinase.	0.972
Avbf_01595	Avbf_12524	A0A444TSH6	A0A444T937	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	Clat_adaptor_s domain-containing protein.	0.683
Avbf_01595	Avbf_12527	A0A444TSH6	A0A444T964	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.683
Avbf_01595	Avbf_13921	A0A444TSH6	A0A444T226	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-4 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.855
Avbf_02723	Avbf_01595	A0A444T7R8	A0A444TSH6	Non-lysosomal glucosylceramidase.	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.971
Avbf_02723	Avbf_03973	A0A444T7R8	A0A444SYM6	Non-lysosomal glucosylceramidase.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.970
Avbf_02723	Avbf_06543	A0A444T7R8	A0A444TQZ2	Non-lysosomal glucosylceramidase.	AP-2 complex subunit mu; Belongs to the adaptor complexes medium subunit family.	0.957
Avbf_02723	Avbf_08180	A0A444T7R8	A0A444SET7	Non-lysosomal glucosylceramidase.	AP-3 complex subunit mu-2; Belongs to the adaptor complexes medium subunit family.	0.953
Avbf_02723	Avbf_08560	A0A444T7R8	A0A444T6T8	Non-lysosomal glucosylceramidase.	AP-3 complex subunit beta-1.	0.967
Avbf_02723	Avbf_08881	A0A444T7R8	A0A444T5B5	Non-lysosomal glucosylceramidase.	Clathrin heavy chain 1.	0.950
Avbf_02723	Avbf_09211	A0A444T7R8	A0A444T5Y5	Non-lysosomal glucosylceramidase.	Cyclin-G-associated kinase.	0.994
Avbf_02723	Avbf_12524	A0A444T7R8	A0A444T937	Non-lysosomal glucosylceramidase.	Clat_adaptor_s domain-containing protein.	0.952
Avbf_02723	Avbf_12527	A0A444T7R8	A0A444T964	Non-lysosomal glucosylceramidase.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.952
Avbf_02723	Avbf_13921	A0A444T7R8	A0A444T226	Non-lysosomal glucosylceramidase.	AP-4 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.957
Avbf_03973	Avbf_01595	A0A444SYM6	A0A444TSH6	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.999

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Network Stats

number of nodes:

11

number of edges:

54

average node degree:

9.82

avg. local clustering coefficient:

0.982

expected number of edges:

14

PPI enrichment p-value:

3.33e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0046168

glycerol-3-phosphate catabolic process

4 of 4

3.27

4.34

1.32e-08

GO:0006116

NADH oxidation

4 of 9

2.92

3.98

4.65e-08

GO:0008654

Phospholipid biosynthetic process

4 of 158

1.67

1.53

0.00041

GO:0019637

Organophosphate metabolic process

6 of 596

1.27

1.29

0.00012

GO:0005975

Carbohydrate metabolic process

6 of 916

1.08

0.92

0.0010

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004367

glycerol-3-phosphate dehydrogenase [NAD+] activity

4 of 4

3.27

4.52

6.19e-09

GO:0051287

NAD binding

4 of 69

2.03

2.21

3.15e-05

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009331

glycerol-3-phosphate dehydrogenase complex

4 of 5

3.17

4.56

4.68e-09

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:21423

Phospholipid/glycerol acyltransferase, and Alditol phosphate metabolic process

5 of 23

2.6

4.32

5.47e-09

CL:21424

Alditol phosphate metabolic process, and Phosphatidate phosphatase activity

4 of 12

2.79

3.68

1.48e-07

CL:21425

glycerol-3-phosphate dehydrogenase complex, and Glycerol kinase

3 of 6

2.97

2.89

5.32e-06

CL:6465

Ubiquitin domain, and Heat shock chaperonin-binding

2 of 10

2.57

1.18

0.0069

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00564

Glycerophospholipid metabolism

5 of 199

1.67

2.12

6.29e-06

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-1483166

Synthesis of PA

5 of 37

2.4

4.02

1.09e-08

MAP-1483206

Glycerophospholipid biosynthesis

5 of 117

1.9

2.64

1.30e-06

MAP-1483257

Phospholipid metabolism

5 of 217

1.63

1.94

1.76e-05

MAP-556833

Metabolism of lipids

5 of 533

1.24

1.07

0.0010

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0009331

glycerol-3-phosphate dehydrogenase complex

4 of 4

3.27

4.62

3.91e-09

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0520

NAD

3 of 56

2.0

1.5

0.0011

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF07479

NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus

3 of 3

3.27

2.97

4.25e-06

PF01210

NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus

2 of 2

3.27

1.58

0.0014

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR011128

Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal

3 of 3

3.27

2.71

1.25e-05

IPR006168

Glycerol-3-phosphate dehydrogenase, NAD-dependent

3 of 3

3.27

2.71

1.25e-05

IPR006109

Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal

3 of 3

3.27

2.71

1.25e-05

IPR013328

6-phosphogluconate dehydrogenase, domain 2

3 of 12

2.67

2.25

7.09e-05

IPR008927

6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily

3 of 22

2.4

1.89

0.00029

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