STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Avbf_10389E3 ubiquitin-protein ligase Topors. (801 aa)    
Predicted Functional Partners:
Avbf_09182
SUMO-conjugating enzyme UBC9-B; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.934
Avbf_07212
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]
   
 
 0.886
Avbf_07856
Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.861
Avbf_15395
Ubiquitin-conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.861
Avbf_13840
UBX domain-containing protein 2.
   
   0.849
Avbf_06938
Cellular tumor antigen p53.
    
 
 0.848
Avbf_02212
Small ubiquitin-related modifier.
    
 0.844
Avbf_00788
Ubiquitin-conjugating enzyme E2 D2B.
    
 0.834
Avbf_03871
Small ubiquitin-related modifier.
    
 0.832
Avbf_10194
Paired amphipathic helix protein Sin3a.
   
 0.748
Your Current Organism:
Armadillidium vulgare
NCBI taxonomy Id: 13347
Other names: A. vulgare, common pillbug
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.