STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Avbf_06925Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (74 aa)    
Predicted Functional Partners:
Avbf_11951
Histone H2A; Belongs to the histone H2A family.
   
 0.943
Avbf_05957
Putative histone-binding protein Caf1.
    
 0.938
Avbf_00772
Core histone macro-H2A.1.
   
 0.935
Avbf_12168
Histone H2A deubiquitinase MYSM1.
    
 0.932
Avbf_10859
Histone acetyltransferase KAT2B.
    
 0.930
Avbf_16357
Histone acetyltransferase type B catalytic subunit.
    
 0.928
Avbf_17138
Histone acetyltransferase type B catalytic subunit.
    
 0.928
Avbf_06149
Histone-lysine N-methyltransferase SETD1.
    
 0.923
Avbf_02874
WD repeat-containing protein 73.
    
 0.922
Avbf_03649
Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
    
 0.921
Your Current Organism:
Armadillidium vulgare
NCBI taxonomy Id: 13347
Other names: A. vulgare, common pillbug
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.