STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysKCysteine synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (308 aa)    
Predicted Functional Partners:
cysE
Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.997
ARC33737.1
Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.982
ARC33738.1
Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.926
serC
Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
  
 
 0.922
cysS
cysteine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.915
luxS
S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
  
 
 0.874
gshAB
Bifunctional glutamate--cysteine ligase/glutathione synthetase; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.
    
 0.872
ARC34375.1
O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.859
A6J79_08110
Tyrosine recombinase XerS; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.829
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
   
 
 0.829
Your Current Organism:
Streptococcus equinus
NCBI taxonomy Id: 1335
Other names: ATCC 33317 [[Streptococcus bovis]], ATCC 9812, CCUG 17828 [[Streptococcus bovis]], CCUG 27302, CCUG 34832 [[Streptococcus bovis]], CIP 102302 [[Streptococcus bovis]], CIP 102504, DSM 20480 [[Streptococcus bovis]], DSM 20558, IFO 12553, JCM 5802 [[Streptococcus bovis]], JCM 7879, LMG 14897, LMG 8518 [[Streptococcus bovis]], LMG:14897, LMG:8518 [[Streptococcus bovis]], NBRC 12553, NCDO 597 [[Streptococcus bovis]], NCIMB 700597 [[Streptococcus bovis]], NCTC 12969, NCTC 8177 [[Streptococcus bovis]], S. equinus, Streptococcus bovis
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