STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARC34015.1LytR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa)    
Predicted Functional Partners:
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
     
 0.795
pheA
Prephenate dehydratase; Catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.789
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
       0.780
codY
GTP-sensing pleiotropic transcriptional regulator CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.
  
   
 0.569
ARC34011.1
L-lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH/MDH superfamily.
       0.555
ARC34306.1
LytR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.527
ARC34010.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0342 family.
       0.500
ARC34009.1
Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.495
ARC33795.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.469
lepB
Signal peptidase I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family.
 
     0.457
Your Current Organism:
Streptococcus equinus
NCBI taxonomy Id: 1335
Other names: ATCC 33317 [[Streptococcus bovis]], ATCC 9812, CCUG 17828 [[Streptococcus bovis]], CCUG 27302, CCUG 34832 [[Streptococcus bovis]], CIP 102302 [[Streptococcus bovis]], CIP 102504, DSM 20480 [[Streptococcus bovis]], DSM 20558, IFO 12553, JCM 5802 [[Streptococcus bovis]], JCM 7879, LMG 14897, LMG 8518 [[Streptococcus bovis]], LMG:14897, LMG:8518 [[Streptococcus bovis]], NBRC 12553, NCDO 597 [[Streptococcus bovis]], NCIMB 700597 [[Streptococcus bovis]], NCTC 12969, NCTC 8177 [[Streptococcus bovis]], S. equinus, Streptococcus bovis
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