STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lepB-2Signal peptidase I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. (185 aa)    
Predicted Functional Partners:
lepB
Signal peptidase I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family.
  
  
 
0.922
lepA
Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
  
 
 0.544
ARC34281.1
AI-2E family transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.525
ARC34280.1
7,8-dihydro-8-oxoguanine triphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.516
ARC34282.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.498
ARC34284.1
Cell wall hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.474
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
    0.461
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
    
  0.460
asnS
asparagine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.459
mutL
Hypothetical protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
   
 
  0.452
Your Current Organism:
Streptococcus equinus
NCBI taxonomy Id: 1335
Other names: ATCC 33317 [[Streptococcus bovis]], ATCC 9812, CCUG 17828 [[Streptococcus bovis]], CCUG 27302, CCUG 34832 [[Streptococcus bovis]], CIP 102302 [[Streptococcus bovis]], CIP 102504, DSM 20480 [[Streptococcus bovis]], DSM 20558, IFO 12553, JCM 5802 [[Streptococcus bovis]], JCM 7879, LMG 14897, LMG 8518 [[Streptococcus bovis]], LMG:14897, LMG:8518 [[Streptococcus bovis]], NBRC 12553, NCDO 597 [[Streptococcus bovis]], NCIMB 700597 [[Streptococcus bovis]], NCTC 12969, NCTC 8177 [[Streptococcus bovis]], S. equinus, Streptococcus bovis
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