STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARC34324.1Histidine phosphatase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate mutase family. (198 aa)    
Predicted Functional Partners:
gpmA
Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
0.925
pgk
Phosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family.
   
 
 0.906
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
     
 0.906
ARC32974.1
Phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.904
gapN
NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; Catalyzes the irreversible NADP-dependent oxidation of glyceraldehyde-3-phosphate to 3-phosphoglycerate. Is not able to use NAD instead of NADP. May play an important role in NADPH production in S.equinus.
   
 
 0.902
ARC33999.1
Glycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycerate kinase type-1 family.
     
  0.900
pgi
Glucose-6-phosphate isomerase; Functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family.
    
 0.818
fba
Fructose-1,6-bisphosphate aldolase, class II; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.812
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.812
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
    
  0.803
Your Current Organism:
Streptococcus equinus
NCBI taxonomy Id: 1335
Other names: ATCC 33317 [[Streptococcus bovis]], ATCC 9812, CCUG 17828 [[Streptococcus bovis]], CCUG 27302, CCUG 34832 [[Streptococcus bovis]], CIP 102302 [[Streptococcus bovis]], CIP 102504, DSM 20480 [[Streptococcus bovis]], DSM 20558, IFO 12553, JCM 5802 [[Streptococcus bovis]], JCM 7879, LMG 14897, LMG 8518 [[Streptococcus bovis]], LMG:14897, LMG:8518 [[Streptococcus bovis]], NBRC 12553, NCDO 597 [[Streptococcus bovis]], NCIMB 700597 [[Streptococcus bovis]], NCTC 12969, NCTC 8177 [[Streptococcus bovis]], S. equinus, Streptococcus bovis
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