STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aqpZAquaporin Z; Protein involved in transporter activity and transport; Belongs to the MIP/aquaporin (TC 1.A.8) family. (216 aa)    
Predicted Functional Partners:
WDC_1097
PTS system, N-acetylglucosamine-specific; Protein involved in protein-N(PI)-phosphohistidine-sugar phosphotransferase activity.
   
  
 0.759
WDC_0024
Protein involved in nucleoside diphosphate kinase activity; Belongs to the NDK family.
  
 
 0.723
prpC
Protein serine/threonine phosphatase PrpC; Regulation of stationary phase.
    
   0.720
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
    
 
 0.675
WDC_1245
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
   0.669
WDC_0640
Transcriptional regulator, Crp/Fnr family; Protein involved in sequence-specific DNA binding transcription factor activity.
   
 0.656
WDC_1826
Transcriptional regulator, Crp/Fnr family; Protein involved in sequence-specific DNA binding transcription factor activity.
   
 0.656
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
  
 
 0.627
glpK-2
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
  
 
 0.627
WDC_0021
Putative oxidoreductase.
    
   0.569
Your Current Organism:
Lactobacillus wasatchensis
NCBI taxonomy Id: 1335616
Other names: DSM 29958, L. wasatchensis, LMG 28678, LMG:28678, Lactobacillus sp. WDC04, Lactobacillus wasatchensis Oberg et al. 2016, strain WDC04
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.