STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fniIsopentenyl-diphosphate delta-isomerase, FMN-dependent; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (346 aa)    
Predicted Functional Partners:
mvaD
Protein involved in diphosphomevalonate decarboxylase activity.
 
  
 0.997
mvaK
Protein involved in phosphomevalonate kinase activity.
 
 0.995
mvk
Protein involved in mevalonate kinase activity.
 
  
 0.973
guaA-2
Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.964
ispB
Octaprenyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
  
 
 0.957
pyk
Protein involved in pyruvate kinase activity; Belongs to the pyruvate kinase family.
  
 0.948
mvaS
Protein involved in hydroxymethylglutaryl-CoA synthase activity.
 
 
 0.882
mvaA
Protein involved in hydroxymethylglutaryl-CoA reductase (NADPH) activity; Belongs to the HMG-CoA reductase family.
   
 0.834
yoaA
ATP-dependent helicase DinG; 3'-5' exonuclease.
  
    0.619
WDC_1006
Alcohol dehydrogenase; Acetaldehyde dehydrogenase; Protein involved in alcohol dehydrogenase (NAD) activity and acetaldehyde dehydrogenase (acetylating) activity; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.590
Your Current Organism:
Lactobacillus wasatchensis
NCBI taxonomy Id: 1335616
Other names: DSM 29958, L. wasatchensis, LMG 28678, LMG:28678, Lactobacillus sp. WDC04, Lactobacillus wasatchensis Oberg et al. 2016, strain WDC04
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