STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WDC_0706Hypothetical protein. (553 aa)    
Predicted Functional Partners:
WDC_0707
Hypothetical protein.
 
     0.883
WDC_0708
Hypothetical protein.
 
   
 0.880
addA
ATP-dependent nuclease, subunit A; ATP-dependent DNA helicase.
  
 
 0.784
dnaN
DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.759
WDC_0711
Electron transfer flavoprotein-ubiquinone oxidoreductase.
  
     0.746
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.713
uvrD
ATP-dependent DNA helicase UvrD.
  
 
 0.671
recQ
ATP-dependent DNA helicase RecQ; Protein involved in nucleic acid binding, helicase activity, ATP binding and ATP-dependent helicase activity.
  
 
 0.626
recS
ATP-dependent DNA helicase RecS.
  
 
 0.626
WDC_0710
DNA-damage-inducible gene.
  
   
 0.602
Your Current Organism:
Lactobacillus wasatchensis
NCBI taxonomy Id: 1335616
Other names: DSM 29958, L. wasatchensis, LMG 28678, LMG:28678, Lactobacillus sp. WDC04, Lactobacillus wasatchensis Oberg et al. 2016, strain WDC04
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.