node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ddl | ftsI | SPICUR_07620 | SPICUR_07665 | Hypothetical protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.922 |
ddl | ftsQ | SPICUR_07620 | SPICUR_07615 | Hypothetical protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Hypothetical protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.964 |
ddl | ftsW | SPICUR_07620 | SPICUR_07640 | Hypothetical protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Hypothetical protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.947 |
ddl | ftsZ | SPICUR_07620 | SPICUR_07605 | Hypothetical protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Peptidase M23; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.850 |
ddl | mraY | SPICUR_07620 | SPICUR_07650 | Hypothetical protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.968 |
ddl | murC | SPICUR_07620 | SPICUR_07630 | Hypothetical protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Hypothetical protein; Cell wall formation; Belongs to the MurCDEF family. | 0.999 |
ddl | murD | SPICUR_07620 | SPICUR_07645 | Hypothetical protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Hypothetical protein; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.980 |
ddl | murE | SPICUR_07620 | SPICUR_07660 | Hypothetical protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Hypothetical protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.948 |
ddl | murF | SPICUR_07620 | SPICUR_07655 | Hypothetical protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Hypothetical protein; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.999 |
ddl | murG | SPICUR_07620 | SPICUR_07635 | Hypothetical protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Hypothetical protein; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.980 |
ftsI | ddl | SPICUR_07665 | SPICUR_07620 | Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Hypothetical protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.922 |
ftsI | ftsQ | SPICUR_07665 | SPICUR_07615 | Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Hypothetical protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.953 |
ftsI | ftsW | SPICUR_07665 | SPICUR_07640 | Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Hypothetical protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.993 |
ftsI | ftsZ | SPICUR_07665 | SPICUR_07605 | Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Peptidase M23; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.784 |
ftsI | mraY | SPICUR_07665 | SPICUR_07650 | Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.992 |
ftsI | murC | SPICUR_07665 | SPICUR_07630 | Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Hypothetical protein; Cell wall formation; Belongs to the MurCDEF family. | 0.946 |
ftsI | murD | SPICUR_07665 | SPICUR_07645 | Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Hypothetical protein; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.992 |
ftsI | murE | SPICUR_07665 | SPICUR_07660 | Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Hypothetical protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.989 |
ftsI | murF | SPICUR_07665 | SPICUR_07655 | Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Hypothetical protein; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.966 |
ftsI | murG | SPICUR_07665 | SPICUR_07635 | Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Hypothetical protein; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.955 |