STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folE2GTP cyclohydrolase I; Converts GTP to 7,8-dihydroneopterin triphosphate. (269 aa)    
Predicted Functional Partners:
SER72783.1
6-pyruvoyltetrahydropterin/6- carboxytetrahydropterin synthase.
    
 0.936
SER39244.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
  
  0.909
ribB
3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
     
 0.901
SER09996.1
PAS domain S-box-containing protein.
    
  0.893
SER29412.1
2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase.
    
 0.786
SEQ89585.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
  
  0.689
SER51235.1
Ribonucleoside-diphosphate reductase alpha chain; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
    
  0.679
SER53347.1
D-erythro-7,8-dihydroneopterin triphosphate epimerase.
    
  0.656
SER53244.1
Dihydroneopterin aldolase.
    
  0.629
dxs
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
       0.618
Your Current Organism:
Nitrosomonas sp. Nm51
NCBI taxonomy Id: 133720
Other names: N. sp. Nm51, Nitrosomonas sp. NM 51
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