STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDY60861.1Isocitrate dehydrogenase. (416 aa)    
Predicted Functional Partners:
SDZ07701.1
Aconitate hydratase.
 
 0.991
SDY23169.1
2-oxoglutarate dehydrogenase E1 component.
   
 
 0.986
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 
 0.959
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
0.958
SDY23198.1
Citrate synthase; Belongs to the citrate synthase family.
 
 0.958
SDY84200.1
Aconitate hydratase.
  
 0.950
SDY14308.1
Glutamate dehydrogenase (NADP+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.941
SDY23364.1
Alanine-synthesizing transaminase.
   
 
 0.923
SDY85043.1
Aspartate aminotransferase.
   
 
 0.923
argH
Argininosuccinate lyase.
     
 0.920
Your Current Organism:
Nitrosomonas sp. Nm33
NCBI taxonomy Id: 133724
Other names: N. sp. Nm33
Server load: low (24%) [HD]