STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKG20800.16-pyruvoyl tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)    
Predicted Functional Partners:
queE
Radical SAM protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
 
 
 0.984
folE
GTP cyclohydrolase 1; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.970
folE-2
GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.970
queC
7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
  
  
 0.945
AKG20058.1
Alkaline phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
AKG20225.1
Alkaline phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
AKG20267.1
Alkaline phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
queF
7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
  
  
 0.824
AKG24192.1
Ribonucleoside-triphosphate reductase; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
  
  
 0.807
cysS
cysteinyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.558
Your Current Organism:
Calothrix sp. 3363
NCBI taxonomy Id: 1337936
Other names: C. sp. 336/3, Calothrix sp. 336/3
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.