STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARC25877.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)    
Predicted Functional Partners:
ARC25878.1
Nucleoid-associated bacterial family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.845
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.810
prmC
protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
     
 0.734
tdk
Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.721
ywlC
threonylcarbamoyl-AMP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SUA5 family.
     
 0.714
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
     
 0.707
ARC26990.1
Cro/Cl family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.694
ARC27280.1
Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.691
ARC26688.1
Copper ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.648
ARC26871.1
Superoxide dismutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.599
Your Current Organism:
Streptococcus intermedius
NCBI taxonomy Id: 1338
Other names: ATCC 27335, CCUG 17827, CCUG 32759, CIP 103248, DSM 20573, JCM 12996, LMG 17840, LMG:17840, NCDO 2227, NCTC 11324, S. intermedius, VPI 3372A, strain SK 54, strain SK54
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