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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGP53402.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (384 aa)    
Predicted Functional Partners:
AGP53404.1
Toxin; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
     0.876
AGP53403.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
     0.866
AGP53401.1
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
     0.809
AGP52949.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
     0.764
AGP59722.1
Von Willebrand factor type A; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
     0.741
AGP60370.1
Exonuclease; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
     0.736
AGP52182.1
Peptidase M9; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
     0.722
AGP56058.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
     0.718
AGP57629.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
     0.718
AGP52644.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
     0.700
Your Current Organism:
Streptomyces rapamycinicus
NCBI taxonomy Id: 1343740
Other names: S. rapamycinicus NRRL 5491, Streptomyces rapamycinicus NRRL 5491
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.