STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGP56454.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (604 aa)    
Predicted Functional Partners:
AGP55316.1
Alkyl hydroperoxide reductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 0.906
msrA
Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
 0.898
AGP56602.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.854
AGP54132.1
NADH dehydrogenase subunit F; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.811
AGP56455.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.739
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.712
AGP54574.1
Vitamin B12-dependent ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
 
 0.653
AGP55118.1
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 
 0.653
AGP58522.1
Cytochrome C oxidase subunit II; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
   
 
 0.653
AGP58211.1
Superoxide dismutase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
   
 0.626
Your Current Organism:
Streptomyces rapamycinicus
NCBI taxonomy Id: 1343740
Other names: S. rapamycinicus NRRL 5491, Streptomyces rapamycinicus NRRL 5491
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.