STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIR64747.1Predicted metal-dependent hydrolase, TIM-barrel fold. (365 aa)    
Predicted Functional Partners:
SIR64884.1
2,3-dihydroxybiphenyl 1,2-dioxygenase.
 
  
  0.713
SIR64846.1
3-(3-hydroxy-phenyl)propionate hydroxylase.
 
  
 0.699
SIR64764.1
Drug resistance transporter, EmrB/QacA subfamily.
       0.598
SIR64833.1
Transcriptional regulator, TetR family.
 
     0.581
SIR98976.1
Hypothetical protein.
  
     0.563
SIR64814.1
2-oxo-3-hexenedioate decarboxylase/2-keto-4-pentenoate hydratase.
     
 0.537
SIR64782.1
4-hydroxy 2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
     
 0.510
SIR64795.1
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
       0.501
SIR61148.1
HD domain-containing protein.
  
     0.474
SIR64864.1
2-hydroxy-6-oxonona-2,4-dienedioate hydrolase/4,5:9,10-diseco-3-hydroxy-5,9, 17-trioxoandrosta-1(10),2-diene-4-oate hydrolase.
 
   
 0.436
Your Current Organism:
Williamsia sterculiae
NCBI taxonomy Id: 1344003
Other names: CPCC 203464, DSM 45741, KCTC 29118, W. sterculiae, Williamsia sp. I12A-00824, Williamsia sp. I12A-01109, Williamsia sterculiae Fang et al. 2013, strain I12A-01109
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