STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIR68563.1Transcriptional regulator, AbiEi antitoxin, Type IV TA system. (312 aa)    
Predicted Functional Partners:
SIR78443.1
Cystathionine beta-synthase.
 
  
  0.671
SIR88768.1
Hypothetical protein.
  
     0.512
SIS08208.1
Transcription regulator of the Arc/MetJ class.
  
     0.506
SIS20181.1
Glutamate synthase (NADH) large subunit.
   
    0.487
SIS21515.1
Glutamate synthase (NADH) large subunit.
   
    0.487
SIR88757.1
Hypothetical protein.
  
     0.485
SIR78383.1
Protein of unknown function.
  
     0.463
SIR65071.1
Protein of unknown function.
  
     0.459
SIS03561.1
Protein of unknown function.
  
     0.445
recB
Exodeoxyribonuclease V beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and rep [...]
 
     0.439
Your Current Organism:
Williamsia sterculiae
NCBI taxonomy Id: 1344003
Other names: CPCC 203464, DSM 45741, KCTC 29118, W. sterculiae, Williamsia sp. I12A-00824, Williamsia sp. I12A-01109, Williamsia sterculiae Fang et al. 2013, strain I12A-01109
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