A0A139A5U7 protein (Gonapodya prolifera) - STRING interaction network

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Known Interactions

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Predicted Interactions

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Score

A0A139A5U7

ARM repeat-containing protein. (1345 aa)

Predicted Functional Partners:

A0A139AXS8

0.964

A0A139AKN7

0.962

A0A139AIT5

0.743

A0A139ALU7

0.743

A0A139ATT1

0.743

A0A139AV43

0.743

A0A139APP2

0.735

A0A139AMS8

0.733

A0A139AZA2

0.698

A0A139AM46

0.680

Your Current Organism:

Gonapodya prolifera

NCBI taxonomy Id: 1344416
Other names: G. prolifera JEL478, Gonapodya prolifera JEL478

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A139A5U7	A0A139AIT5	ARM repeat-containing protein.	Carbonic anhydrase.	0.743
A0A139A5U7	A0A139AKN7	ARM repeat-containing protein.	ADP-ribosylation factor-like protein 2; Belongs to the small GTPase superfamily. Arf family.	0.962
A0A139A5U7	A0A139ALU7	ARM repeat-containing protein.	Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.	0.743
A0A139A5U7	A0A139AM46	ARM repeat-containing protein.	Tubulin-specific chaperone A; Belongs to the TBCA family.	0.680
A0A139A5U7	A0A139AMS8	ARM repeat-containing protein.	DNA-binding protein.	0.733
A0A139A5U7	A0A139APP2	ARM repeat-containing protein.	C-CAP/cofactor C-like domain-containing protein.	0.735
A0A139A5U7	A0A139ATT1	ARM repeat-containing protein.	Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.	0.743
A0A139A5U7	A0A139AV43	ARM repeat-containing protein.	Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.	0.743
A0A139A5U7	A0A139AXS8	ARM repeat-containing protein.	RNI-like protein.	0.964
A0A139A5U7	A0A139AZA2	ARM repeat-containing protein.	Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family.	0.698
A0A139AIT5	A0A139A5U7	Carbonic anhydrase.	ARM repeat-containing protein.	0.743
A0A139AKN7	A0A139A5U7	ADP-ribosylation factor-like protein 2; Belongs to the small GTPase superfamily. Arf family.	ARM repeat-containing protein.	0.962
A0A139AKN7	A0A139AM46	ADP-ribosylation factor-like protein 2; Belongs to the small GTPase superfamily. Arf family.	Tubulin-specific chaperone A; Belongs to the TBCA family.	0.509
A0A139AKN7	A0A139APP2	ADP-ribosylation factor-like protein 2; Belongs to the small GTPase superfamily. Arf family.	C-CAP/cofactor C-like domain-containing protein.	0.590
A0A139AKN7	A0A139AXS8	ADP-ribosylation factor-like protein 2; Belongs to the small GTPase superfamily. Arf family.	RNI-like protein.	0.589
A0A139ALU7	A0A139A5U7	Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.	ARM repeat-containing protein.	0.743
A0A139AM46	A0A139A5U7	Tubulin-specific chaperone A; Belongs to the TBCA family.	ARM repeat-containing protein.	0.680
A0A139AM46	A0A139AKN7	Tubulin-specific chaperone A; Belongs to the TBCA family.	ADP-ribosylation factor-like protein 2; Belongs to the small GTPase superfamily. Arf family.	0.509
A0A139AM46	A0A139APP2	Tubulin-specific chaperone A; Belongs to the TBCA family.	C-CAP/cofactor C-like domain-containing protein.	0.524
A0A139AM46	A0A139AXS8	Tubulin-specific chaperone A; Belongs to the TBCA family.	RNI-like protein.	0.818

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

44

average node degree:

8

avg. local clustering coefficient:

0.866

expected number of edges:

24

PPI enrichment p-value:

0.000217

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0045292

mRNA cis splicing, via spliceosome

10 of 112

1.65

3.65

3.18e-13

GO:0008380

RNA splicing

11 of 163

1.53

3.23

7.19e-14

GO:0006397

mRNA processing

11 of 200

1.44

2.81

3.18e-13

GO:0000393

Spliceosomal conformational changes to generate catalytic conformation

3 of 15

2.0

1.54

0.00092

GO:0000350

Generation of catalytic spliceosome for second transesterification step

2 of 5

2.3

1.04

0.0120

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005681

Spliceosomal complex

11 of 124

1.65

3.98

1.02e-15

GO:0005684

U2-type spliceosomal complex

7 of 63

1.75

3.16

3.42e-09

GO:0000974

Prp19 complex

4 of 18

2.05

2.46

8.61e-06

GO:0071013

Catalytic step 2 spliceosome

5 of 45

1.75

2.3

3.70e-06

GO:0071014

post-mRNA release spliceosomal complex

4 of 46

1.64

1.62

0.00020

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3953

Mixed, incl. Prp19 complex, and Spliceosomal conformational changes to generate catalytic conformation

9 of 28

2.21

6.52

4.78e-16

CL:3955

Prp19 complex, and Saf4/Yju2 protein

7 of 18

2.29

5.7

4.71e-13

CL:3843

mRNA Splicing

10 of 96

1.72

4.16

1.10e-14

CL:3979

Mixed, incl. Saf4/Yju2 protein, and CBF1-interacting co-repressor CIR, N-terminal domain

4 of 5

2.6

3.72

9.12e-08

CL:3838

mRNA Splicing, and Nucleotide-binding alpha-beta plait domain superfamily

11 of 176

1.5

3.17

1.10e-14

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03040

Spliceosome

8 of 126

1.5

2.56

2.03e-09

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-72163

mRNA Splicing - Major Pathway

9 of 102

1.65

3.35

1.73e-11

MAP-72172

mRNA Splicing

9 of 115

1.59

3.17

1.73e-11

MAP-72203

Processing of Capped Intron-Containing Pre-mRNA

10 of 194

1.41

2.54

1.73e-11

MAP-159236

Transport of Mature mRNA derived from an Intron-Containing Transcript

4 of 44

1.66

1.59

0.00027

MAP-72202

Transport of Mature Transcript to Cytoplasm

4 of 50

1.6

1.5

0.00036

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005681

Spliceosomal complex

9 of 97

1.67

3.45

1.16e-11

GOCC:0005684

U2-type spliceosomal complex

6 of 52

1.76

2.71

2.00e-07

GOCC:0000974

Prp19 complex

3 of 16

1.97

1.52

0.00099

GOCC:0071013

Catalytic step 2 spliceosome

2 of 11

1.96

0.77

0.0352

GOCC:0032991

Protein-containing complex

11 of 1692

0.51

0.43

0.00050

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