A0A139ADR8 protein (Gonapodya prolifera) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

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Experiments

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[Homology]

Score

A0A139ADR8

Uncharacterized protein. (79 aa)

Predicted Functional Partners:

A0A139AJ94

0.518

A0A139AYL4

0.499

A0A138ZX06

0.486

A0A138ZYX2

0.472

A0A139A4C3

0.470

A0A139A3V9

0.469

A0A139AFB5

0.469

A0A139ARU9

0.466

A0A139AFH0

0.461

A0A139A7A4

0.454

Your Current Organism:

Gonapodya prolifera

NCBI taxonomy Id: 1344416
Other names: G. prolifera JEL478, Gonapodya prolifera JEL478

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A138ZX06	A0A139ADR8	Uncharacterized protein.	Uncharacterized protein.	0.486
A0A138ZYX2	A0A139ADR8	FAD/NAD(P)-binding domain-containing protein.	Uncharacterized protein.	0.472
A0A138ZYX2	A0A139AJ94	FAD/NAD(P)-binding domain-containing protein.	TPR_REGION domain-containing protein.	0.518
A0A139A3V9	A0A139ADR8	FAD/NAD(P)-binding domain-containing protein.	Uncharacterized protein.	0.469
A0A139A3V9	A0A139AJ94	FAD/NAD(P)-binding domain-containing protein.	TPR_REGION domain-containing protein.	0.518
A0A139A4C3	A0A139ADR8	FAD/NAD(P)-binding domain-containing protein.	Uncharacterized protein.	0.470
A0A139A4C3	A0A139AJ94	FAD/NAD(P)-binding domain-containing protein.	TPR_REGION domain-containing protein.	0.518
A0A139A7A4	A0A139ADR8	FAD/NAD(P)-binding domain-containing protein.	Uncharacterized protein.	0.454
A0A139A7A4	A0A139AJ94	FAD/NAD(P)-binding domain-containing protein.	TPR_REGION domain-containing protein.	0.518
A0A139ADR8	A0A138ZX06	Uncharacterized protein.	Uncharacterized protein.	0.486
A0A139ADR8	A0A138ZYX2	Uncharacterized protein.	FAD/NAD(P)-binding domain-containing protein.	0.472
A0A139ADR8	A0A139A3V9	Uncharacterized protein.	FAD/NAD(P)-binding domain-containing protein.	0.469
A0A139ADR8	A0A139A4C3	Uncharacterized protein.	FAD/NAD(P)-binding domain-containing protein.	0.470
A0A139ADR8	A0A139A7A4	Uncharacterized protein.	FAD/NAD(P)-binding domain-containing protein.	0.454
A0A139ADR8	A0A139AFB5	Uncharacterized protein.	FAD/NAD(P)-binding domain-containing protein.	0.469
A0A139ADR8	A0A139AFH0	Uncharacterized protein.	FAD/NAD(P)-binding domain-containing protein.	0.461
A0A139ADR8	A0A139AJ94	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.518
A0A139ADR8	A0A139ARU9	Uncharacterized protein.	FAD/NAD(P)-binding domain-containing protein.	0.466
A0A139ADR8	A0A139AYL4	Uncharacterized protein.	FAD/NAD(P)-binding domain-containing protein.	0.499
A0A139AFB5	A0A139ADR8	FAD/NAD(P)-binding domain-containing protein.	Uncharacterized protein.	0.469

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

34

average node degree:

6.18

avg. local clustering coefficient:

0.636

expected number of edges:

15

PPI enrichment p-value:

2.32e-05

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005978

Glycogen biosynthetic process

3 of 8

2.35

1.83

0.00036

GO:0005975

Carbohydrate metabolic process

7 of 326

1.1

1.03

0.00029

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016758

Hexosyltransferase activity

3 of 17

2.02

1.33

0.0027

GO:0102752

1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)

2 of 5

2.37

0.94

0.0186

GO:0003844

1,4-alpha-glucan branching enzyme activity

2 of 5

2.37

0.94

0.0186

GO:0004553

Hydrolase activity, hydrolyzing O-glycosyl compounds

3 of 50

1.55

0.83

0.0186

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005829

Cytosol

5 of 344

0.94

0.57

0.0211

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4821

Starch and sucrose metabolism, and Amino acid/polyamine transporter I

10 of 26

2.36

8.34

9.26e-20

CL:4825

Glycogen metabolic process, and Alpha-amylase domain

6 of 13

2.44

5.31

1.86e-11

CL:4863

Amino acid/polyamine transporter I, and Alpha amylase, catalytic domain

4 of 5

2.68

3.8

7.03e-08

CL:4827

Glycosyl hydrolase, all-beta

4 of 7

2.53

3.55

1.67e-07

CL:4841

Glycogen biosynthesis, and Carbohydrate phosphorylase

2 of 5

2.37

1.21

0.0058

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

pls00500

Starch and sucrose metabolism

7 of 27

2.19

5.23

1.99e-12

pls01110

Biosynthesis of secondary metabolites

6 of 327

1.04

0.94

0.00036

pls01100

Metabolic pathways

7 of 701

0.77

0.62

0.0014

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0031588

Nucleotide-activated protein kinase complex

2 of 6

2.3

0.94

0.0189

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0320

Glycogen biosynthesis

3 of 5

2.55

2.35

4.14e-05

KW-0119

Carbohydrate metabolism

3 of 14

2.1

1.84

0.00025

KW-0321

Glycogen metabolism

2 of 3

2.6

1.57

0.0013

KW-0328

Glycosyltransferase

4 of 69

1.54

1.47

0.00031

KW-0326

Glycosidase

3 of 36

1.69

1.35

0.0013

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00324

Amino acid permease

3 of 3

2.77

2.35

4.81e-05

PF00128

Alpha amylase, catalytic domain

3 of 10

2.25

1.82

0.00034

PF16657

Maltogenic Amylase, C-terminal domain

2 of 2

2.77

1.35

0.0035

PF02806

Alpha amylase, C-terminal all-beta domain

2 of 2

2.77

1.35

0.0035

PF02922

Carbohydrate-binding module 48 (Isoamylase N-terminal domain)

2 of 6

2.3

1.09

0.0097

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR013780

Glycosyl hydrolase, all-beta

5 of 8

2.57

4.17

1.02e-08

IPR006047

Glycosyl hydrolase, family 13, catalytic domain

5 of 12

2.39

3.86

2.44e-08

IPR017853

Glycoside hydrolase superfamily

5 of 27

2.04

2.95

5.23e-07

IPR045857

Oligo-1,6-glucosidase, domain 2

2 of 2

2.77

1.2

0.0066

IPR044143

Glycogen branching enzyme GlgB, N-terminal Early set domain

2 of 2

2.77

1.2

0.0066

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00642

Alpha-amylase domain

2 of 2

2.77

1.5

0.0019

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