STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
A0A1D2VH293-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (365 aa)    
Predicted Functional Partners:
A0A1D2VJ22
3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 0.971
A0A1D2VHF0
Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
 
 0.953
A0A1D2VDP8
Acetolactate synthase.
 0.901
A0A1D2VK93
Acetolactate synthase.
  
 0.881
A0A1D2VNT9
2-isopropylmalate synthase.
 
 0.859
A0A1D2VBB3
Homocitrate synthase isozyme, catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 0.805
A0A1D2VCR9
Threonine dehydratase.
  
 
 0.780
A0A1D2VHV8
Argininosuccinate lyase.
  
 
 0.758
A0A1D2VK07
Dihydroxy-acid and 6-phosphogluconate dehydratase.
  
  
 0.660
A0A1D2VK26
2-oxoglutarate dehydrogenase, E1 component.
   
 0.654
Your Current Organism:
Ascoidea rubescens
NCBI taxonomy Id: 1344418
Other names: A. rubescens DSM 1968, Ascoidea rubescens DSM 1968
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.