STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1D2VNB6Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. (189 aa)    
Predicted Functional Partners:
A0A1D2VIU3
Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.
   
 0.999
A0A1D2VKU6
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
    
 0.999
A0A1D2VB08
Autophagy-related protein 3.
    
 0.996
A0A1D2VDQ4
Autophagy protein 16.
    
 0.993
A0A1D2VJI9
Pkinase-domain-containing protein.
    
 
 0.976
A0A1D2VJQ3
Autophagy-related protein.
   
 0.935
A0A1D2V9J3
Autophagy_act_C domain-containing protein.
    
 0.915
A0A1D2VGB7
Alpha/beta-hydrolase.
   
 
 0.884
A0A1D2VGZ0
Alpha/beta-hydrolase.
   
 
 0.884
A0A1D2VL72
APG6-domain-containing protein.
   
 0.869
Your Current Organism:
Ascoidea rubescens
NCBI taxonomy Id: 1344418
Other names: A. rubescens DSM 1968, Ascoidea rubescens DSM 1968
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.