STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OI25_1110Band 3 cytoplasmic domain protein; [GT] COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type). (151 aa)    
Predicted Functional Partners:
ptsP
PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase; [G] COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria).
 
  
 0.898
OI25_1172
PTS_HPr_: phosphocarrier, HPr family protein; [G] COG1925 Phosphotransferase system, HPr-related proteins.
 
  
 0.889
hprK
HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
 
  
 0.880
raiA
yfiA: ribosomal subunit interface protein; [J] COG1544 Ribosome-associated protein Y (PSrp-1).
  
  
 0.863
ptsP-2
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.857
OI25_1112
P-loop ATPase family protein; Displays ATPase and GTPase activities.
  
  
 0.847
nagE
PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component; [G] COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.
 
  
 0.759
OI25_1173
[G] COG2893 Phosphotransferase system, mannose/fructose-specific component IIA.
 
  
 0.755
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.691
OI25_1192
deoR-like helix-turn-helix domain protein; [KG] COG1349 Transcriptional regulators of sugar metabolism.
 
  
 0.648
Your Current Organism:
Paraburkholderia fungorum
NCBI taxonomy Id: 134537
Other names: ATCC BAA-463, Burkholderia fungorum, Burkholderia fungorum Coenye et al. 2001, Burkholderia sp. LMG 16225, Burkholderia sp. LMG 16307, Burkholderia sp. LMG16225, Burkholderia sp. LMG16307, CCUG 31961, CIP 107096, DSM 17061, JCM 21562, LMG 16225, LMG:16225, NBRC 102489, P. fungorum, Paraburkholderia fungorum (Coenye et al. 2001) Sawana et al. 2015, strain Croize P763-2
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