STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OI25_1234Metallo-beta-lactamase superfamily protein; [R] COG0491 Zn-dependent hydrolases, including glyoxylases. (356 aa)    
Predicted Functional Partners:
OI25_1583
neuD_NnaD: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family protein; [R] COG0110 Acetyltransferase (isoleucine patch superfamily).
  
    0.754
OI25_3570
Rhs_assc_core: RHS repeat-associated core domain protein; [M] COG3209 Rhs family protein.
   
    0.698
OI25_5163
[M] COG3209 Rhs family protein.
   
    0.698
OI25_1235
merR regulatory family protein; [K] COG0789 Predicted transcriptional regulators.
 
  
 0.644
OI25_5820
Beta-lactamase family protein; [V] COG2367 Beta-lactamase class A.
      
 0.536
OI25_6192
Beta-lactamase family protein; [V] COG2367 Beta-lactamase class A.
      
 0.536
aceK
Isocitrate dehydrogenase kinase/phosphatase family protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
       0.533
chrA
2A51: chromate efflux transporter family protein; [P] COG2059 Chromate transport protein ChrA.
     
 0.516
arsH
resist_ArsH: arsenical resistance protein ArsH; [R] COG0431 Predicted flavoprotein.
      
 0.516
chrA-2
2A51: chromate efflux transporter family protein; [P] COG2059 Chromate transport protein ChrA.
     
 0.516
Your Current Organism:
Paraburkholderia fungorum
NCBI taxonomy Id: 134537
Other names: ATCC BAA-463, Burkholderia fungorum, Burkholderia fungorum Coenye et al. 2001, Burkholderia sp. LMG 16225, Burkholderia sp. LMG 16307, Burkholderia sp. LMG16225, Burkholderia sp. LMG16307, CCUG 31961, CIP 107096, DSM 17061, JCM 21562, LMG 16225, LMG:16225, NBRC 102489, P. fungorum, Paraburkholderia fungorum (Coenye et al. 2001) Sawana et al. 2015, strain Croize P763-2
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