STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OI25_3762[F] COG1957 Inosine-uridine nucleoside N-ribohydrolase. (373 aa)    
Predicted Functional Partners:
amn
AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.
 
  
 0.932
OI25_6432
Hypothetical protein; 5'-nucleotidase, C-terminal domain protein; [F] COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family.
 
 
  0.929
OI25_4158
[F] COG1957 Inosine-uridine nucleoside N-ribohydrolase.
  
  
 
0.928
OI25_6672
[F] COG1957 Inosine-uridine nucleoside N-ribohydrolase.
  
  
 
0.928
add-2
Aden_deam: adenosine deaminase; [F] COG1816 Adenosine deaminase.
 
 
 0.923
OI25_1977
[F] COG0634 Hypoxanthine-guanine phosphoribosyltransferase.
  
  
 0.921
OI25_3209
Amidohydrolase family protein; [F] COG1001 Adenine deaminase.
 
  
  0.921
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
 0.914
OI25_1987
pfkB carbohydrate kinase family protein; [G] COG0524 Sugar kinases, ribokinase family.
  
 
 0.913
add
Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
  
 
 0.908
Your Current Organism:
Paraburkholderia fungorum
NCBI taxonomy Id: 134537
Other names: ATCC BAA-463, Burkholderia fungorum, Burkholderia fungorum Coenye et al. 2001, Burkholderia sp. LMG 16225, Burkholderia sp. LMG 16307, Burkholderia sp. LMG16225, Burkholderia sp. LMG16307, CCUG 31961, CIP 107096, DSM 17061, JCM 21562, LMG 16225, LMG:16225, NBRC 102489, P. fungorum, Paraburkholderia fungorum (Coenye et al. 2001) Sawana et al. 2015, strain Croize P763-2
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