STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OI25_6878SPFH domain / Band 7 family protein; [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs. (257 aa)    
Predicted Functional Partners:
OI25_6879
Hypothetical protein; nfeD-like C-terminal, partner-binding family protein; [O] COG1030 Membrane-bound serine protease (ClpP class).
 
  
 0.968
hflB
ATP-dependent metallopeptidase HflB family protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.672
OI25_4633
ATPase associated with various cellular activities family protein; [O] COG0465 ATP-dependent Zn proteases; Belongs to the AAA ATPase family.
   
 0.672
hflB-2
ftsH_fam: ATP-dependent metallopeptidase HflB family protein; [O] COG0465 ATP-dependent Zn proteases.
   
 0.672
OI25_6880
[K] COG2207 AraC-type DNA-binding domain-containing proteins.
  
    0.558
hflK
HflK protein; HflC and HflK could encode or regulate a protease.
  
   
 0.540
OI25_5253
Putative membrane protein.
   
 0.488
OI25_6877
Hypothetical protein.
       0.485
OI25_2939
[R] COG0666 FOG: Ankyrin repeat.
 
 
 0.434
OI25_6881
Hypothetical protein; acyl-CoA dehydrogenase, N-terminal domain protein; [I] COG1960 Acyl-CoA dehydrogenases.
  
   0.419
Your Current Organism:
Paraburkholderia fungorum
NCBI taxonomy Id: 134537
Other names: ATCC BAA-463, Burkholderia fungorum, Burkholderia fungorum Coenye et al. 2001, Burkholderia sp. LMG 16225, Burkholderia sp. LMG 16307, Burkholderia sp. LMG16225, Burkholderia sp. LMG16307, CCUG 31961, CIP 107096, DSM 17061, JCM 21562, LMG 16225, LMG:16225, NBRC 102489, P. fungorum, Paraburkholderia fungorum (Coenye et al. 2001) Sawana et al. 2015, strain Croize P763-2
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